Inducción anestésica : cambios hemodinámicos con el uso de etomidato y fentanyl

Tesis de grado (Especialista en Anestesiología) -- Universidad Central de Venezuela. Facultad de Medicina. Comisión de Estudios de Postgrado., oct. 1992.

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A comparison of the hemodynamics effects during induction of anesthesia, of ethomidate and the combination of ethomidate and the combination of ethomidate/fentanyl was done in 60 patients. Patients were ASA I-II divided into two groups of 30, for elective surgery. Induction in group A was done with ethomidate (0,3mg/Kg) and fentanyl (2mg/Kg), and in group B with ethomidate withthe same dose. We also compared the quality of intubation, and others daverse effects during induction. Pancourium bromide (0,08/Kg) wasused for intubation. Oxygen 100 por ciento was used with controlled ventilation for 5 minutes after intubation. No significant staticals difference was observed between the two groups concerning blood pressure, both systolic and diastolic, and heart rate, although the major changes were observed in the B group. There was a significant statistical difference when compared the basal values with those 2 minutes after intubation in the two groups. Paint at the side of injection of ethomidate was statistically higher in group B (80 por ciento ). Myoclonia was also statistically significant in group B (83,3 por cent ). We concluded that ethomidate alone, or used in combination with fentanyl cannot supress the hemodinamics effects of laringoscopy, nevertheless the changes in blood pressure end heart still are not higher than 20 per cent of the basal values. The use of fentanyl reduced the incidence of myoclonia and pain at the site of injection(AU)